Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: 214]

Specifications

Product Data
Clone Name	214
Applications	ELISA
Recommend Dilution	ELISA:  This antibody can be used as a Coating antibody in a two site assay with Catalogue Number BM696 as the detection reagent.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Highly pure PSA from Human Prostate.
Specificity	This antibody is specific for Prostate Specific Antigen, recognising both the free and complexed forms
Formulation	PBS, pH 7.0 State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	kallikrein related peptidase 3
Database Link	Entrez Gene 354 Human UniProt ID P07288
Background	Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.
Synonyms	Prostate-specific antigen, Semenogelase, Gamma-seminoprotein, P-30 antigen
Reference Data

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