Apolipoprotein A I (APOA1) Mouse Monoclonal Antibody [Clone ID: G2]

CAT#: BM785

Apolipoprotein A I (APOA1) mouse monoclonal antibody, clone G2, Purified



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CNY 7,912.00


货期*
4周

规格
    • 500 ug

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Specifications

Product Data
Clone Name G2
Applications ELISA
Recommend Dilution ELISA (1/2.500-1/10.000). This antibody is suitable for coating microtitre plates in a Sandwich ELISA using catalogue number BP912HRP for detection.
Western Blot (1/250-1/1000).
Immunohistochemistry on Frozen Sections (1/20-1/80).
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Native Human Apolipoprotein A1 from Human plasma.
Specificity Reacts with both free Apolipoprotein A1 and HDL bearing Apo-A1. Does not cross-react with ApoE, ApoB or Albumin.
Formulation 0.01M Sodium Phosphate, 0.01M Sodium Borate, 0.15M Sodium Chloride with 1% Mannitol and 1% Dextran.
State: Purified
State: Lyophilized purified IgG fraction
Reconstitution Method Restore with 1.0 ml distilled water.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store the lyophilized antibody at 2-8°C and after reconstitution at -20°C.
Avoid repeated freezing and thawing.
Gene Name apolipoprotein A1
Background Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease.
The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Synonyms APOA1, ApoA-I, Apo-AI, ApoAI
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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