VC1456 Rabbit Polyclonal Antibody

CAT#: BP2193

VC1456 rabbit polyclonal antibody, Purified



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CNY 11,569.00


货期*
5周

规格
    • 1 ml

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Specifications

Product Data
Applications ELISA, IP
Recommend Dilution ELISA: Titer: >1:1,000.
Also suitable for conjugation purposes.
Immunoprecipitates toxin in gel techniques.
Reactivity Vibrio cholerae
Host Rabbit
Clonality Polyclonal
Immunogen Purified choleragenoid.
Specificity Beta subunit of Cholera toxin.
Formulation 0.01M PBS, pH 7.2 with 0.09% sodium azide as preservative.
State: Purified
State: Liquid purified Ig fraction (>95% pure) .
Concentration lot specific
Purification Protein A chromatography.
Conjugation Unconjugated
Storage Condition Store the antibody at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing.
Background The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
Synonyms Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB, VC_1456
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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