GFAP Guinea Pig Polyclonal Antibody
CAT#: BP5082
GFAP guinea pig polyclonal antibody, Serum
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CNY 5,830.00
货期*
5周
规格
Cited in 2 publications. |
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | Immunoblotting (Western): 1/2000. Cytological Material. Immunohistochemistry on Frozen Sections: 1/100 Immunohistochemistry on Paraffin-Embedded Tissue: 1/50. Incubation time: 1 h at RT, extended with Paraffin. |
Reactivity | Bovine, Human, Rat |
Host | Guinea Pig |
Clonality | Polyclonal |
Immunogen | Gliafilament protein purified from Bovine spinal cord. |
Specificity | Specific detection of Gliafilament protein (Mr 52000 polypeptide). Tumors Specifically Detected: Astrocytomas, gangliomas, meulloblastomas, certain teratomas. |
Formulation | State: Serum State: Whole Antiserum with 0.09% Sodium Azide and 0.5% BSA |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C. |
Predicted Protein Size | 50 kDa (Predicted) |
Gene Name | glial fibrillary acidic protein |
Database Link | |
Background | Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes. |
Synonyms | Glial Fibrillary Acidic Protein |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
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Cell type- and region-specific enhancement of adult hippocampal neurogenesis by daidzein in middle-aged female mice.
,null,
Neuropharmacology
,PubMed ID 27580847
[GFAP]
|
Intrauterine valproate exposure is associated with alterations in hippocampal cell numbers and folate metabolism in a rat model of valproate teratogenicity
,Semmler A, Frisch C, Bleul C, Smith D, Bigler L, Prost JC, Blom H, Linnebank M,
Seizure
,PubMed ID 28212902
[GFAP]
|
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