CDK5 Mouse Monoclonal Antibody [Clone ID: OTI2H6]

Specifications

Product Data
Clone Name	OTI2H6
Applications	FC, IF, WB
Recommend Dilution	WB 1:1000~2000, IF 1:50~100, FLOW 1:100
Reactivity	Human, Dog, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human CDK5 (NP_004926) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	33.3 kDa
Gene Name	cyclin dependent kinase 5
Database Link	NP_004926 Entrez Gene 12568 MouseEntrez Gene 140908 RatEntrez Gene 475537 DogEntrez Gene 1020 Human UniProt ID Q00535
Background	Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
Synonyms	PSSALRE
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Alzheimer's disease, Axon guidance

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