ALK Rat Monoclonal Antibody [Clone ID: OTI1D9]

CAT#: CF801141

Carrier-free (BSA/glycerol-free) ALK rat monoclonal antibody, clone OTI1D9 (formerly 1D9)

Formulation: Standard Carrier-Free



  View other "OTI1D9" antibodies (4)

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CNY 3,999.00


货期*
2周

规格
    • 100 ug

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经常一起买 (2)
Biotinylation Labelling Kit formatted 4 x 0.05mg
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HRP Conjugation kit for 0.2mg IgG
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Specifications

Product Data
Clone Name OTI1D9
Applications LMNX, WB
Recommend Dilution WB 1:2000
Reactivity Human, Mouse, Rat
Host Rat
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1060-1620 of human ALK (NP_004295)produced in SF9 Cell.
Formulation Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 176.3 kDa
Gene Name ALK receptor tyrosine kinase
Background This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X). [provided by RefSeq, Jan 2011]
Synonyms CD246; NBLST3
Reference Data
Protein Families Druggable Genome, Protein Kinase
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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