NR2E3 Mouse Monoclonal Antibody [Clone ID: OTI3D4]

Specifications

Product Data
Clone Name	OTI3D4
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human NR2E3 (NP_057430) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39.5 kDa
Gene Name	nuclear receptor subfamily 2 group E member 3
Database Link	NP_057430 Entrez Gene 23958 MouseEntrez Gene 100365683 RatEntrez Gene 10002 Human UniProt ID Q9Y5X4
Background	This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul
Synonyms	ESCS; PNR; rd7; RNR; RP37
Reference Data
Protein Families	Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

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