Neurofilament (NEFL) (+ Neurofilament H) Mouse Monoclonal Antibody [Clone ID: 2F11]

CAT#: DM080X

Neurofilament (NEFL) (+ Neurofilament H) mouse monoclonal antibody, clone 2F11, Supernatant



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CNY 5,236.00


货期*
4周

规格
    • 1 ml

Product images

Specifications

Product Data
Clone Name 2F11
Applications IHC, WB
Recommend Dilution Western Blot.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
Use Polymer anti Mouse/Rabbit IgG as a detection system.
Positive Control: Brain.
Reactivity Feline, Human, Mouse, Opossum, Rabbit, Rat
Host Mouse
Clonality Monoclonal
Immunogen Neurofilament purified from Human brain.
Specificity 2F11 labels neurons, neuronal processes, and peripheral nerves as well as sympathetic ganglion cells and adrenal medulla. Cell body of neurons, containing the non-phosphorylated neurofilament, is weakly stained.
Cellular Localization: Cytoplasmic.
Formulation State: Supernatant
State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Gene Name neurofilament, light polypeptide
Background Neurofilaments are the intermediate filaments of neurons and their processes. They are protein triplets composed of three major subunits of MW 68kDa, 155kDa, and 200kDa. Neurofilaments are expressed in tumors of neural origin, or displaying neuronal differentiation, such as neuroblastoma, medulloblastoma, and retinoblastoma.
Synonyms NF-L,NEFL, NF68, 68 kDa neurofilament protein
Note Mol. Wt. of Antigen: 68kDa and 200kDa (phosphorylated forms of these subunits).
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS
Protein Pathways Amyotrophic lateral sclerosis (ALS)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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