CEACAM7 Mouse Monoclonal Antibody [Clone ID: BAC2]

Specifications

Product Data
Clone Name	BAC2
Applications	ELISA, FC, IF, IHC
Recommend Dilution	ELISA: 1/200-1/400. Cell based ELISA with intakt, transiently transfected cells: 1/200. Flow cytometry: 1.2 µg/106 cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CEACAM7/Fc fusion protein
Specificity	This antibody recognizes CEACAM7.
Formulation	Phosphate buffered saline, pH 7.2 without preservatives State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	carcinoembryonic antigen related cell adhesion molecule 7
Database Link	Entrez Gene 1087 Human UniProt ID Q14002
Background	CEA-related cell adhesion molecule 7 (CEACAM7, CGM2) belongs to the carcinoembryonic antigen (CEA) family (1). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts (2). CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon (2). Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A domain.
Synonyms	CGM2
Reference Data

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