Herpes Virus Type 8 / HHV8 Rat Monoclonal Antibody [Clone ID: LN53]

CAT#: DM395

Herpes Virus Type 8 / HHV8 rat monoclonal antibody, clone LN53, Purified



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CNY 8,775.00


货期*
4周

规格
    • 1 ml

Product images

Specifications

Product Data
Clone Name LN53
Applications IHC
Recommend Dilution Immunohistochemistry: Use at 1/25-1/50 dilution in an ABC method (30 to 60 minutes at room temperature).
Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Recommended Positive Control: Kaposi's sarcoma.
Reactivity Human
Host Rat
Clonality Monoclonal
Immunogen Recombinant protein corresponding to the latent nuclear antigen-1 molecule of HHV8.
Specificity This antibody stains with ORF-73 of Human Herpesvirus 8 (HHV8). HHV8 is the likely etiological agent of Kaposi's sarcoma (KS). HHV8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity.
Cellular Localization: Nuclear.
Formulation State: Purified
State: Liquid purified Tissue Culture Supernatant
Preservative: 0.09% Sodium Azide
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C.
Background HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.
Synonyms HHV-8, KHSV
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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