Cxcl10 Rabbit Polyclonal Antibody

CAT#: PP1083P1

Cxcl10 rabbit polyclonal antibody, Aff - Purified

Conjugation: Unconjugated Biotin



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PP1083P1 is a possible alternative to TA328523.

CNY 3,910.00


货期*
5周

规格
    • 50 ug

Product images

Specifications

Product Data
Applications ELISA, WB
Recommend Dilution Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Mouse IP-10 (100 ng/ml), a concentration of 10.0 µg/ml of this antibody is required.
Sandwich ELISA: To detect Mouse IP-10 by Sandwich ELISA (using 100 ml/well antibody solution), a concentration of 0.5-2.0 µg/ml of this antibody is required. This Biotinylated antibody, in conjuction with anti Mouse IP10 antibody (cat. PP1083B) as a Detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Mouse IP-10.
Western Blot: To detect Mouse IP-10 by Western Blot analysis this antibody can be used at a concentration of 0.1 -0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Mouse IP-10 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Highly pure (>98%) E.coli derived recombinant Mouse IP-10.
Specificity Reacts with Interferon-gamma Inducible Protein-10
Formulation PBS, pH 7.2 without preservatives
State: Aff - Purified
State: Lyophilized (sterile filtered) purified Ig fraction
Reconstitution Method Restore in sterile water to a concentration of 0.1-1.0 mg/ml.
Purification Affinity Chromatography using an immobilizedd Murine IP-10 Matrix
Conjugation Unconjugated
Storage Condition Store the antibody prior to reconstitution at -20°C. Following reconstitution the antibody can be stored at 2-8°C for one month or at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name chemokine (C-X-C motif) ligand 10
Background Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.
Synonyms C-X-C motif chemokine 10, Small-inducible cytokine B10, Gamma-IP10, INP10, SCYB10
Note Centrifuge vial prior to opening!
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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