FSH beta (FSHB) (beta 2 epitope) Mouse Monoclonal Antibody [Clone ID: INN-hFSH-60]

Specifications

Product Data
Clone Name	INN-hFSH-60
Applications	ELISA, IHC
Recommend Dilution	Immunohistochemistry on frozen and paraffin embedded sections (recommended positive control: Pituitary Gland). ELISA (in combination with antibody SM1466P it can be used to detect holo-hFSH bound to a solid phase).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human FSH
Specificity	The antibody is directed against the beta 2 epitope of the beta subunit of FSH. Shows strong reactions with FSH and beta-FSH, but no cross-reactivity with TSH, LH, HCG, alph-HCG or alpha-FSH. The recognition site is located near the alpha 1 binding site on the hFSH molecule. It is not compatible with other anti-hFSH-beta antibodies.
Formulation	PBS, pH 7.4, containing 0.09% sodium azide State: Aff - Purified State: Liquid IgG fraction
Concentration	lot specific
Purification	Protein A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	follicle stimulating hormone beta subunit
Database Link	Entrez Gene 2488 Human UniProt ID P01225
Background	Follicle stimulating hormone enables ovarian folliculogenesis to the antral follicle stage and is essential for Sertoli cell proliferation and maintenance of sperm quality in the testis. Members of the pituitary glycoprotein hormone family, of which FSH is one consist of a shared alpha chain and a beta chain encoded by a separate gene. The FSH beta gene encodes the beta subunit of follicle stimulating hormone.
Synonyms	Follitropin beta chain, FSHB, FSH beta
Reference Data

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