MADCAM1 Mouse Monoclonal Antibody [Clone ID: 314G8]

CAT#: SM2237P

MADCAM1 mouse monoclonal antibody, clone 314G8, Purified

Size: 100 ug 200 ug

Conjugation: Unconjugated Biotin



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CNY 6,116.00


货期*
4周

规格
    • 200 ug

Cited in 3 publications.

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Specifications

Product Data
Clone Name 314G8
Applications ELISA, IHC
Recommend Dilution ELISA.
Immunohistochemistry on Frozen sections: 1/25-1/1000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant soluble MAdCAM-1-fc fusion protein.
Spleen cells from immunised Balb/c mice were fused with cells of the mouse P3X63Ag8.653 myeloma cell line.
Specificity This antibody recognises Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM-1).
MAdCAM-1 expression has also been reported in the gut lamina propria but Clone 314G8 does not recognise MAdCAM-1 in these tissues.
Clone 314G8 reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognised by clone 314G8.
Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7. We recommend the use of SM2237LE for this purpose.
Formulation PBS
State: Purified
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Preservative: 0.09% Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name mucosal vascular addressin cell adhesion molecule 1
Background MAdCAM-1 is a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria.
Synonyms hMAdCAM-1, MAdCAM-1, Mucosal addressin cell adhesion molecule 1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (3)

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