Fas Ligand (FASLG) Mouse Monoclonal Antibody [Clone ID: 14C2]

Specifications

Product Data
Clone Name	14C2
Applications	ELISA, FC, IP
Recommend Dilution	Flow Cytometry: 1/25 - 1/50; use 10 µl of the suggested working dilution to label 106 cells in 100 µl. ELISA. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line.
Specificity	This antibody recognises the CD178 cell surface antigen. This antibody may be used in combination with clone 10F2 (SM2268P) in ELISA assays. Clone 14C2 is not reported to have a blocking function. We recommend the use of SM2268LE for functional studies.
Formulation	PBS, pH7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Fas ligand
Database Link	Entrez Gene 356 Human UniProt ID P48023
Background	CD178 is a 40kDa glycoprotein also known as Fas ligand (CD95L). CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form. CD178 plays an important role in T cell development cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.
Synonyms	FASLG, APT1LG1, FASL, TNFSF6, CD95L protein, APTL
Reference Data

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