Ptprc (CD45RA) Mouse Monoclonal Antibody [Clone ID: OX-33]

CAT#: SM279PS

Ptprc (CD45RA) mouse monoclonal antibody, clone OX-33, Purified

Size: 100 ug 250 ug



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CNY 4,587.00


货期*
4周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name OX-33
Applications FC, IHC
Recommend Dilution Flow Cytometry: 1/50 - 1/100; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Immunohistochemistry on frozen and paraffin sections.
Reactivity Rat
Host Mouse
Clonality Monoclonal
Immunogen Purified rat spleen leucocyte common antigen. Spleen cells from immunised BALB/c mice were fused with cells of the NSO/U myeloma cell line.
Specificity This antibody is directed against a high molecular weight band of the leucocyte common antigen (LCA). MRC OX-33 only labels B-cells among thoracic duct lymphocytes with little labelling in bone marrow and none on thymocytes.
Formulation PBS, pH7.2 containing 0.09% Sodium Azide
State: Purified
State: Liquid purified IgG
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name protein tyrosine phosphatase, receptor type, C
Background CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoforms (220, 205, 190, 180 kDa) which share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc.
Synonyms PTPRC, Leukocyte common antigen, L-CA, T200
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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