CD9 Mouse Monoclonal Antibody [Clone ID: IVA50]

Specifications

Product Data
Clone Name	IVA50
Applications	FC, FN, IP, WB
Recommend Dilution	Flow cytometry. Immunoprecipitation. Western blotting. Functional application (the antibody activates bovine thrombocytes).
Reactivity	Bovine
Host	Mouse
Clonality	Monoclonal
Immunogen	Bovine thrombocytes
Specificity	Clone IVA50 reacts with CD9 antigen, a 24 kDa single transmembrane polypeptide expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
Formulation	PBS, pH 7.4, with 15 mM sodium azide as preservative State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A affinity chromatography ( > 95% by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Database Link	Entrez Gene 280746 Bovine UniProt ID P30932
Background	CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
Synonyms	MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen
Reference Data

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