ENT1 (SLC29A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	This ENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the Central region of human ENT1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50219 Da
Gene Name	solute carrier family 29 member 1 (Augustine blood group)
Database Link	NP_004946 Entrez Gene 63959 MouseEntrez Gene 63997 RatEntrez Gene 2030 Human UniProt ID Q99808
Background	ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
Synonyms	ENT1
Reference Data
Protein Families	Transmembrane

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