EIF4A1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:10~50
Reactivity	Human, Mouse, Bovine, Monkey
Host	Rabbit
Clonality	Polyclonal
Immunogen	This EIF4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human EIF4A1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46154 Da
Gene Name	eukaryotic translation initiation factor 4A1
Database Link	NP_001407 Entrez Gene 13681 MouseEntrez Gene 106993879 MonkeyEntrez Gene 1973 Human UniProt ID P60842
Background	EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Synonyms	DDX2A; EIF-4A; eIF-4A-I; EIF4A; eIF4A-I
Reference Data

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