Prohibitin (PHB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	WB: 1:1000, IHC: 1:50~100, FC: 1:10~50
Reactivity	Human, Bovine, Chicken
Host	Rabbit
Clonality	Polyclonal
Immunogen	This Prohibitin (PHB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the N-terminal region of human Prohibitin (PHB1).
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	29804 Da
Gene Name	prohibitin
Database Link	NP_002625 Entrez Gene 5245 Human UniProt ID P35232
Background	Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.
Synonyms	HEL-215; HEL-S-54e; PHB1
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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