KDM2B Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC, PEP-ELISA
Recommend Dilution	WB: 1-3ug/ml.
Reactivity	Human, Mouse, Rat, Dog
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-FGQVEEKLLQKLS, from the C Terminus of the protein sequence according to NP_115979.3.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lysine demethylase 2B
Database Link	NP_001005366 Entrez Gene 30841 MouseEntrez Gene 304495 RatEntrez Gene 486262 DogEntrez Gene 84678 Human UniProt ID Q8NHM5
Background	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq]
Synonyms	CXXC2; Fbl10; FBXL10; JHDM1B; PCCX2
Reference Data
Protein Families	Druggable Genome

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