GBA Rabbit Polyclonal Antibody

CAT#: TA308241

Rabbit polyclonal antibody to beta-glucosidase (glucosidase, beta; acid (includes glucosylceramidase))



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CNY 6,281.00


货期*
4周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human, Chimpanzee
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 65 and 384 of GBA (Uniprot ID#P04062)
Formulation 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 60 kDa
Gene Name glucosylceramidase beta
Background This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
Synonyms acid (includes glucosylceramidase); beta; D-glucosyl-N-acylsphingosine glucohydrolase; GBA1; GCB; GLUC; glucocerebrosidase; glucocerebrosidase (alt.); glucosidase; lysosomal glucocerebrosidase; OTTHUMP00000033992; OTTHUMP00000033993
Note Seq homology of immunogen across species: Chimpanzee (100%)
Reference Data
Protein Families Druggable Genome
Protein Pathways Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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