TCP1 epsilon (CCT5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:10000
Reactivity	Human, Rhesus Monkey, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 89 and 338 of TCP1 epsilon (Uniprot ID#P48643)
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	60 kDa
Gene Name	chaperonin containing TCP1 subunit 5
Database Link	NP_036205 Entrez Gene 12465 MouseEntrez Gene 22948 Human UniProt ID P48643
Background	This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
Synonyms	CCT-epsilon; CCTE; HEL-S-69; PNAS-102; TCP-1-epsilon
Note	Seq homology of immunogen across species: Rhesus Monkey (100%)
Reference Data
Protein Families	Druggable Genome

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