SEC61A (SEC61A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Rat, Zebrafish, Xenopus, Dog, Pig, Bovine, Rhesus Monkey, X. tropicalis, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 413 and 476 of SEC61A1
Formulation	1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52 kDa
Gene Name	Sec61 translocon alpha 1 subunit
Database Link	NP_037468 Entrez Gene 53421 MouseEntrez Gene 80843 RatEntrez Gene 404006 DogEntrez Gene 29927 Human UniProt ID P61619
Background	The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq]
Synonyms	HSEC61; SEC61; SEC61A
Note	Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (93%), Xenopus Tropicalis (100%), Dog (100%), Pig (100%), Rhesus Monkey (100%), Bovine (100%)
Reference Data
Protein Families	Transmembrane
Protein Pathways	Vibrio cholerae infection

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