Glutathione Peroxidase 2 (GPX2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	IHC:1:100-1:1000; WB:1:100-1:1000
Reactivity	Human, Dog, Pig, Rabbit, Chimpanzee, Bovine, Rhesus Monkey, X. tropicalis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region within amino acids 1 and 54 of GPX2
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22 kDa
Gene Name	glutathione peroxidase 2
Database Link	NP_002074 Entrez Gene 480356 DogEntrez Gene 2877 Human UniProt ID P18283
Background	This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. [provided by RefSeq]
Synonyms	GI-GPx; GPRP; GPRP-2; GPx-2; GPx-GI; GSHPx-2; GSHPX-GI
Note	Seq homology of immunogen across species: Xenopus Tropicalis (80%), Dog (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Arachidonic acid metabolism, Glutathione metabolism

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