AGR2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Hamster
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal AGR2 antibody was raised against a 17 amino acid peptide near the amino terminus of human AGR2.
Formulation	AGR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	AGR2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	19 kDa
Gene Name	anterior gradient 2, protein disulphide isomerase family member
Database Link	NP_006399 Entrez Gene 10551 Human UniProt ID O95994
Background	AGR2 Antibody: AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours. AGR2 is ubiquitously expressed with upregulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR).
Synonyms	AG2; GOB-4; HAG-2; HEL-S-116; PDIA17; XAG-2
Reference Data
Protein Families	Secreted Protein

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