MAP126 (SPAG5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 979-1174 amino acids of human sperm associated antigen 5
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	sperm associated antigen 5
Database Link	NP_006452 Entrez Gene 54141 MouseEntrez Gene 10615 Human UniProt ID Q96R06
Background	Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene. This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles.?Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment; normal timing of sister chromatid segregation; and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Synonyms	DEEPEST; hMAP126; MAP126
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency

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