IL23 Receptor (IL23R) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human sigmoid tissue IHC: 5-20 Positive control: Human rectal cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 31-227 amino acids of Human Interleukin-23 receptor
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	72 kDa
Gene Name	interleukin 23 receptor
Database Link	NP_653302 Entrez Gene 149233 Human UniProt ID Q5VWK5
Background	The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1; and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2); and also binds to transcription activator STAT3 in a ligand-dependent manner.
Synonyms	interleukin 23 receptor; OTTHUMP00000010660
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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