B3galt5 Rat Monoclonal Antibody [Clone ID: MC-631]

CAT#: TA336273

Rat Monoclonal SSEA-3 Antibody (MC-631)



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CNY 5,381.00


货期*
5周

规格
    • 100 ul

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Specifications

Product Data
Clone Name MC-631
Applications CyTOF-ready, FC, ICC/IF, IHC, IP, WB
Recommend Dilution Western Blot: 1:500, Immunohistochemistry-Paraffin: 1:10-1:500, CyTOF-ready, Immunohistochemistry-Frozen: 1:10-1:500, Flow Cytometry: 10-20 ug/ml, Immunohistochemistry: 1:10-1:500, Immunocytochemistry/ Immunofluorescence: 1:50-1:100, Immunoprecipitation: 1:10-1:500
Reactivity Human, Mouse
Host Rat
Clonality Monoclonal
Immunogen 4-8 cell stage mouse embryos.
Formulation Tris-glycine, 150mM NaCl pH 7.5, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification IgM purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
Background SSEA-3 (stage-specific embryonic antigen-3) is a member of SSEAs which are present on eggs as well as preimplantation embryos at specific stages of early development. SSEAs are glycan epitopes which resides on glycoproteins/glycolipids of mammalian cells, and the epitope of several of these antigens consists solely of sugar residues. SSEA-3 antigen was identified following immunization of rats with 4-8 cell mouse embryos and was present on glycolipids of human teratocarcinoma cells. During protein glycosylation, beta-1,3-galactosyltransferase 5 catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside GB4, thereby synthesizing glycolipid GB5 which is SSEA-3. In its functions. SSEA-3 has been proposed to involve in the process of cell differentiation. SSEA3 expression is mostly restricted to the cytoplasm or apical surface of epithelial cells and it has been reported to express in various normal tissues with high expression levels in kidney. SSEA3 has been reported to be expressed in the ascites fluids from patients of hepatoma or pancreatic cancer, breast cancer including breast cancer stem cells.
Synonyms b3Gal-T5; B3GalT-V; B3GalTx; B3T5; Beta-3-Gx-T5; beta3Gal-T5; GLCT5; OTTHUMP00000109186
Note This SSEA3 antibody is useful for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry frozen and paraffin sections, Immunoprecipitation and Western Blot.
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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