IKB alpha (NFKBIA) Mouse Monoclonal Antibody [Clone ID: 6A920]

CAT#: TA336372

Mouse Monoclonal IkB-alpha Antibody (6A920)



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CNY 5,521.00


货期*
5周

规格
    • 100 ug

经常一起买 (4)
Transient overexpression lysate of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA)
    • 100 ug

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Recombinant protein of human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA), 20 µg
    • 20 ug

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Recombinant protein of human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA), 100 µg
    • 100 ug

CNY 9,998.00

Specifications

Product Data
Clone Name 6A920
Applications CyTOF-ready, FC, ICC/IF, IHC, IP, Simple Western, WB
Recommend Dilution Flow Cytometry: 0.25-1 ug/10^6 cells, Immunoprecipitation: 1 ug/ml, Western Blot: 1-2 ug/ml, Immunohistochemistry: 1:20-1:1000, Simple Western: 1:20, Immunohistochemistry-Paraffin: 1:100, Immunocytochemistry/ Immunofluorescence: 1:100-1:1000, Knockout Validated, CyTOF-ready
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Immunogen A recombinant protein corresponding to amino acid residues 32-291 of human IkBa was used as immunogen.
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein G purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name NFKB inhibitor alpha
Background NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB (1). Synthesis of IkBa is autoregulated (2). IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/a, IKK2/b, and IKK3/g (3-6). External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified (1). One of the first gene induced following NF-kB activation is IkBa.
Synonyms IKBA; MAD-3; NFKBI
Reference Data
Protein Families Druggable Genome
Protein Pathways Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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