IGF2R Mouse Monoclonal Antibody [Clone ID: 2G11]

CAT#: TA336637

Mouse Monoclonal IGF-II R/Mannose 6 Phosphate Receptor (Cation independent) Antibody (2G11)



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CNY 5,521.00


货期*
5周

规格
    • 100 ul

经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

CNY 300.00
CNY 1,430.00

Specifications

Product Data
Clone Name 2G11
Applications CyTOF-ready, ELISA, FC, ICC/IF, IHC, IP, WB
Recommend Dilution Flow Cytometry: 1 ug per million cells, ELISA, Immunohistochemistry: 1:100, Immunocytochemistry/ Immunofluorescence: 1:10-1:250, Immunoprecipitation: 1:10-1:500, Western Blot: 1 ug/ml, Immunohistochemistry-Paraffin: 1:100, CyTOF-ready
Reactivity Human, Rat, Bovine, Primate
Host Mouse
Clonality Monoclonal
Immunogen Purified bovine Mannose 6 Phosphate Receptor (Cation independent) [UniProt# P08169]
Formulation PBS containing 0.05% BSA, 0.05% Sodium Azide. Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration lot specific
Purification Protein A purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name insulin like growth factor 2 receptor
Background Mannose 6 phosphate is a sequence tag that plays a pivotal role in delivering proteins to the lysosome. Specifically, the mannose 6 phosphate sequence is tagged to N-linked oligosaccharides of lysosomal hydrolases as they pass through the cis-Golgi network. Once the lysosomal enzymes are tagged with the M6P sequence, they are destined to the late endosome by way of vesicular transport. After a low pH dissociates the M6P Receptor from its ligand, the M6P sequences are recycled. Additionally, M6P is bound by lectin in the immune system, and is converted to fructose 6-phosphate by mannose phosphate isomerase.
Synonyms CD222; CIMPR; M6P-R; MPR1; MPRI
Note By Western Blot, a 300 kDa protein representing Mannose 6 Phosphate Receptor is seen in HeLa cell extract under non-reducing conditions. Immunofluorescence staining of Mannose 6 Phosphate Receptor in HeLa cells with this antibody results in perinuclear staining. This antibody is also useful in Flow Cytometry, Immunoprecipitation, ELISA and Immunohistochemistry-on parraffin embedded sections.
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Lysosome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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