SOX4 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	ELISA (1:100 ?? 1:1,000); Western blotting (1:4,000)
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-SOX4 antibody: human SOX4 (SRY (sex determining region Y)-box 4), using two KLH-conjugated synthetic peptides containing a sequence from the N-terminus and from the C-terminus of the protein, respectively.
Concentration	lot specific
Purification	Whole antiserum from rabbit containing 0.05% azide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	SRY-box 4
Database Link	NP_003098 Entrez Gene 6659 Human UniProt ID Q06945
Background	SOX4 (UniProtKB/Swiss-Prot entry Q06945) belongs to the SOX family of transcription factors. These transcription factors are characterized by the conserved HMG (high mobility group) DNA binding domain and are involved in embryonic development. SOX4 has been shown to be important for the development of the cardiac outflow tract and of the central nervous system. SOX 4 may also be involved in the apoptosis pathway were it can either lead to cell death or to tumorigenesis, and has been associated with several human cancer types.
Synonyms	EVI16
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors

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