CDK7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:3000
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen for anti-CDK7 Antibody: A synthesized peptide derived from human CDK7
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration	lot specific
Purification	Affinity-chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	39 kDa
Gene Name	cyclin-dependent kinase 7
Database Link	NP_001790 Entrez Gene 12572 MouseEntrez Gene 1022 Human UniProt ID P50613
Background	CDK7 a protein kinase of the CDK family. Forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). Activates the cyclin-associated kinases CDK1, -2, -4 and -6. An essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. Serves as a direct link between the regulation of transcription and the cell cycle
Synonyms	CAK1; CDKN7; HCAK; MO15; p39MO15; STK1
Note	CDK7 antibody detects endogenous levels of total CDK7
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Stem cell - Pluripotency, Transcription Factors
Protein Pathways	Cell cycle, Nucleotide excision repair

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