CACNA1H Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CACNA1H antibody was raised against a 16 amino acid peptide near the center of human CACNA1H.
Formulation	PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CACNA1H antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 259 kDa; Observed: 260 kDa
Gene Name	calcium voltage-gated channel subunit alpha1 H
Database Link	NP_066921 Entrez Gene 8912 Human UniProt ID O95180
Background	The calcium channel protein CACNA1H is a T-type member of the alpha-1 subunit family that is part of the voltage-dependent calcium channel complex which mediates the influx of calcium ions into the cell upon membrane polarization (1,2). CACNA1H is a subunit of Cav3.2 T-type calcium channel that is involved in neurological disorders such as epilepsy and pain (2,3). CACNA1H associates with the caveolin protein Cav-3 and it is thought that Cav-3 regulates the Protein Kinase A (PKA) modulation of CACNA1H-containing Cav3.2 T-type calcium channels (4).
Synonyms	CACNA1HB; Cav3.2; ECA6; EIG6; HALD4
Reference Data

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