CCR5 Rabbit Polyclonal Antibody

CAT#: TA351039

Rabbit Polyclonal Anti-CCR5 Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Product images

经常一起买 (2)
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Transient overexpression lysate of chemokine (C-C motif) receptor 5 (CCR5), transcript variant A
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications IHC
Recommend Dilution IHC: 25-100
Positive control: Human Lymphoma
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide of human CCR5
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name C-C motif chemokine receptor 5 (gene/pseudogene)
Background This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.
Synonyms CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane
Protein Pathways Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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