GLP1 (GCG) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against GLP-1 (7- 37). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Bovine, Guinea Pig, Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Hys-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser- Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly- Arg-Gly-OH coupled to carrier protein.
Formulation	This polyclonal antibody is supplied as a lyophilized powder. The powder should be rehydrated with 50ml of RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4° - 8°C. This should ensure antibody stability for approximately one month.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	glucagon
Database Link	Entrez Gene 2641 Human UniProt ID P01275
Background	Glucagon-Like Peptide-1 (GLP-1) (7-37) is an incretin hormone that causes glucose dependent release of insulin by pancreatic beta cells. It derives from the proteolytic cleavage of proglucagon, which gives rise to two biologically active forms, GLP-1 (7- 36) and GLP-1 (7-37). Both play roles in gastric motility on the suppression of plasma glucagon levels and promote the stimulation of glucose disposal in peripheral tissues independent of the actions of insulin. This antibody was generated by immunization of rabbits with GLP-1 (7-37) coupled to a carrier protein.
Synonyms	GLP1; GLP2; glucagon; GRPP
Reference Data

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