BAD Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/30 FC: 1/50
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human Bad
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	23kDa
Gene Name	BCL2 associated agonist of cell death
Database Link	Entrez Gene 572 Human UniProt ID Q92934
Background	Swiss-Prot Acc.Q92934.Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Synonyms	BBC2; BBC6; Bcl2-L-8; BCL2L8
Reference Data

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