DOHH Rabbit Monoclonal Antibody [Clone ID: R04-4I8]

Specifications

Product Data
Clone Name	R04-4I8
Applications	IP, WB
Recommend Dilution	WB: 1/1000 IP: 1/20
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human DOHH
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 33 kDa; Observed MW: 33 kDa
Gene Name	deoxyhypusine hydroxylase/monooxygenase
Database Link	Entrez Gene 83475 Human UniProt ID Q9BU89
Background	Swiss-Prot Acc.Q9BU89.Catalyzes the hydroxylation of the N6-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function .
Synonyms	hDOHH; HLRC1; MGC4293
Reference Data

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