RbAp48 (RBBP4) Rabbit Monoclonal Antibody [Clone ID: R07-5D6]

Specifications

Product Data
Clone Name	R07-5D6
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/2000-1/10000 IHC: 1/20 ICC/IF: 1/20 IP: 1/20
Reactivity	Human, Mouse, Rat, Hamster
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human RbAp48
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 48 kDa; Observed MW: 48 kDa
Gene Name	RB binding protein 4, chromatin remodeling factor
Database Link	Entrez Gene 5928 Human UniProt ID Q09028
Background	Swiss-Prot Acc.Q09028.Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
Synonyms	NURF55; RBAP48; RBBP-4
Reference Data

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