S100 beta (S100B) Rabbit Monoclonal Antibody [Clone ID: R01-1F9]
CAT#: TA385204
S100B Rabbit monoclonal Antibody
Size: 20 ul
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Specifications
Product Data | |
Clone Name | R01-1F9 |
Applications | IHC, IP, WB |
Recommend Dilution | WB: 1/1000 IHC: 1/50-1/200 IP: 1/20 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human S100 beta |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | Calculated MW: 11 kDa; Observed MW: 11 kDa |
Gene Name | S100 calcium binding protein B |
Database Link | |
Background | Swiss-Prot Acc.P04271.Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. |
Synonyms | NEF; OTTHUMP00000174958; S100; S100beta |
Reference Data |
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