Rbpms Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, ICC, IHC, WB
Recommend Dilution	WB: 1:1000 ICC: 1:200-1:500
Reactivity	Feline, Guinea Pig, Pig, Human, Mouse, Rabbit, Rat, Tree Shrew, Whale, Zebrafish
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat RBPMS, conjugated to keyhole limpet hemocyanin (KLH).
Specificity	Specific for endogenous levels of the ~24 kDa RBPMS protein.
Formulation	PBS + 0.03% NaN3
Concentration	lot specific
Purification	Antigen Affinity Purified
Conjugation	Unconjugated
Storage Condition	Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Predicted Protein Size	24
Gene Name	RNA binding protein gene with multiple splicing
Database Link	Entrez Gene 19663 Mouse UniProt ID Q93062
Background	RBPMS (RNA binding protein with multiple splicing), also known as HERMES, contains one RRM (RNA recognition motif) domain and belongs to the RRM family of RNA-binding proteins. RBPMS exists as multiple alternatively spliced isoforms and is thought to bind RNA, possibly playing a role in RNA-related events, such as transcription and translation. RNA-binding proteins that are specific to retinal ganglion cells (RGCs) have been previously identified as excellent markers for RGCs (Kwong et al., 2010). Recent findings show that antibodies against RBPMS are robust reagents that exclusively identify RGCs in multiple mammalian species (Rodriguez et al. 2014)
Synonyms	HERMES; RBP-MS
Note	Affinity purification of serum via chromatography on an affinity column prepared with the peptide used as antigen.
Reference Data

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