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glucose 6 phosphatase, catalytic subunit (G6PC) Rabbit Monoclonal Antibody [Clone ID: OTIR5G10]
CAT＃: TA592780
G6PC Rabbit monoclonal antibody,clone OTIR5G10
Size: 30 ul
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Specifications
| Product Data | |
| Clone Name | OTIR5G10 |
| Applications | IHC, WB |
| Recommend Dilution | WB 1:2000, IHC 1:300-1:1500 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal |
| Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human G6PC (NP_000142). The exact sequence is proprietary. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws. |
| Predicted Protein Size | 40.5 kDa |
| Gene Name | glucose-6-phosphatase catalytic subunit 1 |
| Database Link | |
| Background | Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011] |
| Synonyms | G6Pase; G6PC; G6PT; GSD1; GSD1a |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Adipocytokine signaling pathway, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism |
Documents
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| TA592780S | G6PC Rabbit monoclonal antibody,clone OTIR5G10 |
CNY 870.00 |
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