NAPSIN A (NAPSA) Mouse Monoclonal Antibody [Clone ID: OTI3E5]

Specifications

Product Data
Clone Name	OTI3E5
Applications	IF, IHC
Recommend Dilution	IHC 1:150
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 64-244 of human NAPSA(NP_004842) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	42.7 kDa
Gene Name	napsin A aspartic peptidase
Database Link	NP_004842 Entrez Gene 9476 Human UniProt ID O96009
Background	The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus. [provided by RefSeq, Jul 2008]
Synonyms	KAP; Kdap; NAP1; NAPA; SNAPA
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Lysosome

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