VILIP1 (VSNL1) Mouse Monoclonal Antibody [Clone ID: UMAB115]

Specifications

Product Data
Clone Name	UMAB115
Applications	IF, IHC, WB
Recommend Dilution	IHC 1:200
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 2-191 of human VSNL1 (NP_003376) produced in E.coli.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22 kDa
Gene Name	visinin like 1
Database Link	NP_003376 Entrez Gene 24877 RatEntrez Gene 26950 MouseEntrez Gene 7447 Human UniProt ID P62760
Background	This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Synonyms	HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1
Reference Data
Protein Families	Druggable Genome

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