Parathyroid Hormone (PTH) Mouse Monoclonal Antibody [Clone ID: UMAB274]

Specifications

Product Data
Clone Name	UMAB274
Applications	IHC
Recommend Dilution	IHC 1:4000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 32-115 of human PTH (NP_000306) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5~1.0 mg/ml (Lot Dependent)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	12.86 kDa
Gene Name	parathyroid hormone
Database Link	NP_000306 Entrez Gene 5741 Human UniProt ID P01270
Background	This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Synonyms	FIH1; PTH1
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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