Human CEACAM5 ELISA Kit 1 x 96

Specifications

Product Data
Description	Human CEACAM5 ELISA Kit 1 x 96
Size	1 x 96 wells
Format	8x12 divisible strips
Assay Type	Sandwich
Assay Length	3.5 hours incubations; 0.5 hour washing and analyzing samples
Signal	Colorimetric
Curve Range	0.313-20ng/ml
Sample Type	Human serum, plasma, and other biological fluids.
Sample Volume	100µl
Specificity	This kit is used for quantitative detection of CEACAM5
Sensitivity	99pg/ml
Reactivity	Human
Cross Reactivity	There is no detectable cross-reactivity with other relevant proteins.
Interference	No significant interference observed with available related molecules.
Components	CEACAM5 MonoclonL Antibody Coated 96-well Plate in foil pouch with desiccant|1 plate Human CEACAM5 Standard (1000ng/ml)|0.1 mL 100x Biotin conjugated CEACAM5 Detection Antibody|0.12 mL 100x SA-HRP Conjugate|0.12 mL Assay Buffer|40 mL Sample Diluent|30 mL Wash Buffer Concentrate 20X|60 mL TMB Substrate|12 mL Stop Solution|12 mL Plate Sealer|3 pieces
Background	Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a member of the carcinoembryonic antigen (CEA) gene family. CEACAM5 is often used as a synonym for cancer embryonic antigen (CEA). It is a well-known biomarker of many types of malignancies, such as colorectal cancer and non-small-cell lung cancer. Its primary function in the embryonic intestine and colon tumors is adhesion between epithelial cells. Also, it plays a significant role in the inhibition of differentiation and apoptosis in colon cells. There are evidences that high CEACAM5 expression is firmly associated with the CD133-positive colorectal cancer stem cells. High CEACAM5 expression has also been identified in ~25% of patients with advanced non-squamous non-small cell lung cancer (NSCLC) detectable via IHC (immunohistochemistry). Elevated levels of CEACAM5 in the serum of colorectal cancer (CRC) patients represent a clinical biomarker that correlates with disease recurrence.
Gene Symbol	CEACAM5
Standard Curve	Data image of Human CEACAM5 ELISA Kit.

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