Human BCA1 (CXCL13) ELISA KIT (96 T)

Specifications

Product Data
Description	Human CXCL13 Immunoassay
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	3.91-250pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant human CXCL13.
Sensitivity	3.5pg/mL
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,1000 pg/ml upon reconstitution,2 vials Concentrated Biotin-Conjugated antibody(100X) - 120 ul/vial,1 vials Concentrated Streptavidin-HRP solution(100X) - 120 ul/vial,1 vial Standard /Sample Diluent - 16 ml/vial,1 bottle Biotin-Conjugate antibody Diluent - 16 ml/vial,1 bottle Streptavidin-HRP Diluent - 16 ml/vial,1 bottle Wash Buffer Concentrate (20x) - 30 ml/vial,1 bottle Substrate Solution - 12 ml/vial,1 bottle Stop Solution - 12 ml/vial,1 bottle Plate Cover Seals,4 pieces
Background	B-Lymphocyte Chemoattractant (BLC), also known as B Cell-Attracting chemokine 1 (BCA-1), or CXCL13, is a member of the CXC subtype of the chemokine superfamily. BLC is critical for secondary lymphoid tissue development and navigation of lymphocytes within the microcompartments of these tissues. The gene encodes a putative protein of 109 amino acids (aa), including a 21 aa leader peptide. At the aa level, human BLC exhibits 64% similarity to its mouse counterpart, and the gene has been mapped to chromosome segment 4q21. Within the human BLC protein sequence, an arginine residue separates the first two of four conserved cysteine residues that are characteristic of CXC chemokines. BLC is a pertussis toxin-sensitive chemoattractant for B cells in vitro. It is constitutively expressed in the B cell follicles of secondary lymphoid organs, and expression of BLC in these structures is dependent upon the activity of lymphotoxin α/β. BLC is also expressed in the pleural and peritoneal cavities, and in ectopic lymphoid follicles found within the synovium of patients with rheumatoid arthritis.
Gene Symbol	CXCL13

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