Mouse Cxcl13 ELISA KIT (96 T)
CNY 3,200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Mouse BLC Immunoassay |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 15.62-1000pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant mouse BLC. |
Sensitivity | 8pg/mL |
Reactivity | Mouse |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | B-Lymphocyte Chemoattractant (BLC), also known as B Cell-Attracting chemokine 1 (BCA-1), or CXCL13, is a constitutively produced 16-18 kDa member of the α-, or CXC family of chemokines. It is synthesized as a 109 amino acid (aa) precursor that contains a 21 aa signal sequence plus an 88 aa mature segment. The mature segment contains four cysteines with no potential N-linked glycosylation sites. In the mature region, mouse BLC/BCA-1 shows only 64% aa similarity and 46% aa identity to human BLC/BCA-1. Among α-chemokines, mature BLC/BCA-1 is only 30% aa identical to mature mouse MIP-2 and KC. Like other chemokines, it is assumed that BLC forms non-disulfide linked homodimers. Cells known to express BLC are varied in type and include salivary gland epithelium, CD11b+CD11c+ dendritic cells, osteoclasts, and peritoneal macrophages. |
Gene Symbol | Cxcl13 |
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