Porcine TGFB1 ELISA KIT (96 T)

CAT#: EA800179

Porcine TGF-β1 Immunoassay



CNY 3,200.00


货期*
3周

规格
    • 96 T

Product images

Specifications

Product Data
Description Porcine TGF-β1 Immunoassay
Size 96 T
Format 96-well strip plate
Assay Type Solid Phase Sandwich ELISA
Assay Length 4 hours
Signal Colorimetric
Curve Range 31.25-2000pg/ml
Sample Type Serum, plasma, Cell culture supernatant
Sample Volume 100 uL
Sensitivity 15 pg/mL
Reactivity Porcine
Interference No significant interference observed with available related molecules.
Components
  • Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate
  • Standard - lyophilized,2000 pg/ml upon reconstitution,2 vials
  • lyophilized Biotin-Conjugated antibody,2 vials
  • Concentrated Streptavidin-HRP,1 vial
  • Standard /Sample Diluent,1 bottle
  • Biotin-Conjugate antibody Diluent,1 bottle
  • Streptavidin-HRP Diluent,1 bottle
  • 20 x Wash Buffer Concentrate,1 bottle
  • Substrate Solution,1 bottle
  • Stop Solution ,1 bottle
  • Plate Cover Seals,4 pieces
  • 1N HCl,1 bottle
  • 1N NaOH,1 bottle
Background TGF-β1 (transforming growth factor beta 1) was first identified in human platelets as a protein with a molecular mass of 25 kilodaltons with a potential role in wound healing. TGF- β1, TGF- β2, and TGF-β3 all function through the same receptor signaling systems. They are members of the large TGF-β superfamily. TGF-β proteins are highly pleiotropic cytokines that regulate processes such as immune function, proliferation and epithelial mesenchymal transition . It was later characterized as a large protein precursor (containing 390 amino acids) that was proteolytically processed to produce a mature peptide of 112 amino acids .TGF-β activation from latency is controlled both spatially and temporally, by multiple pathways that include actions of proteases such as plasmin and MMP9, and/or by thrombospondin 1 or selected integrins . Although different isoforms of TGFβ are naturally associated with their own distinct LAPs, the TGF-β1 LAP is capable of complexing with, and inactivating, all other Porcine TGF-β isoforms and those of most other species . Mutations within the LAP are associated with Camurati Engelmann disease, a rare sclerosing bone dysplasia characterized by inappropriate presence of active TGF-β1 .
Gene Symbol TGFB1
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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