CA8 (NM_004056) Human 3' UTR Clone

Specifications

Product Data
Product Name	CA8 (NM_004056) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CA-RP; CA-VIII; CALS; CAMRQ3; CARP
ACCN	NM_004056
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC212818 3’UTR clone of NM_004056 The sequence shown below is from the reference sequence of NM_004056. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACAGAGTCATTAGAGCTGCATTTCAGTAGCCAAAGAGGACAGGAACAAGTCTGTCTTCATGAGGGAGG AAGACAATGGTCCTATAATGCCCTTGGATAAGAAAAGGAAACTTTTGAGCTGCACCTTCAGTTTATCCT CAAAGCCTGCGTTGTTTGTCTTCATCTAATCCAGCTTTGATGGACATCTGTGATGGTTGCCTGTACACT TGCTGAAATGAAATATTAGAAATGGCTGTATATTCCAAAGAAACCCTATATTATATATCCACATTACTG CTGCTAGGATTCATAGTTGCACATACTGTTTATTGCTTATGTGTAGAAGGAATGAAACTAGTTTCCAGA GTTGTTATTAATATGAATATATATCATGTGTTAATATTGAGAAAGGAAAAATACATTCCCGGTGTTAGT AGTTCTTCATTTCCTGTCTCCAACAGAAAATTCACTCATTTTAGAACTAGTGTAATTCTTGATAATAAA ATAAGAGTTTTGATTAAGAACAGCATAGAGCTTCAAAATGCAAAGTGAATGATTAGTAAAATTATGTCT CATTTTATTTTTTCAGCACCCATACCACAATTAATATTAGGCTGGATTGCCATGGGAAACATTTTTTGG CATTAATGCAGCAACATAATACTCACTTTAGGTATTACTACATAGTTGAAGGATTTAACTGAATGTATG GATCAAATTTATTTATTTGACATATTCGAAGCTGTGGTTTAATAGGAATTTGAGAAAGGTGTAAGAAAT AGGATAAAAAGAAGGTCAGCACCATGTACCAGGAATAGCTTTACTTTCCATACATAGAAATATAAATTT AGTGGTATCCTATATTACTTTAGTGTCGTACGCTTTGTAAGACTTAAATATTTTATTCTATTGATTCCA CTACTTTGGTATGTTAAGACATTTCTTTAAAGATGACCAACAATATCCTTATTTTAGGTGCCACTAGCA GATGTAAGCGTATACTTAGTTGCCGTTAGATGTGACAGAATGAGATAATTTATGTAAAGCAGTAGAGTA CCTGGCACAAAGCAAACAATAAATATTATTGTTATTGTTGTTATAATTGTAAAATGAATGACTTCAAAA ACATAGTCCCAGTTTGGAGGGATTTTGTGATGCAGAATATCTAAGTCATAGAAATAGAAGACAGGTGGA ATAAGTATATGTTCAGAGTTTTTAGATGTGTTGAGTAGAGACGGTAATAATGGAAGCATTAAATACAAA TGAAAATCACACCAGATATCCCTGAAATTCAAGCAAAGAAAGTTCATCATGTATTCTTGGGCAGCAAGA GAAAGGACTAGGGTTATGGCAATGTGTGGAAAAGTTGAGGCTTGCTAAGGGTTGAGATCTGTTGGTAGC CCTGGATCACATGGGGTCAGCACCAGGCAGTGCCTCTGAAAGCGGAGAGAGGTCCTGGACTTCCCTTGT GTATAACAGTTCCTAGTGTCCAACAATGAGGAAACGGTGAAGCATGGTTACAAAACTGTGACAAAAATA TTTACATCTAGCACTGTTACCACTCACATGCCAAACATTGGCTGCACACGTGCAGCCTTATTTGTAATT AACATCAAAAGACTAGATCTGAAGCCTTCCATAAATGAGAGGCCATTCATATGGCATTCCTGGAACAAA ACACTGCACAGGTACCAGCCTCTCCACTCCTGACCGGGTTGGTGCTGAACAGTCAGGGATTGTTCTTGA ACTAGACTTCTGATGCTTCTTGCAATCTTCTTTCATCTTTCCCTGAAATACACAAAATAAACAAATACA ATAACAAATAGTAATTAAATGACTTTCAGGATAACATCTAGTTGTTCAGACTTCACCCTTCACAGGTGT GTGTGTATGTGTGTTTATGTCTGTATATTGAAGCAATTTGAATTTATTTACTGTATATTTTCTGAGTAA AAGACTGAAATGAACTACTTGGTTCAGATCATGGTGTCCATTGGTGACATTGTTTGGAGGCATAATAT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004056.6
Synonyms	CA-RP; CA-VIII; CALS; CAMRQ3; CARP
Summary	The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Locus ID	767
MW	76.6

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