TRAF4 (NM_004295) Human Tagged Lenti ORF Clone
CAT#: RC200345L4
- LentiORF®
Lenti ORF clone of Human TNF receptor-associated factor 4 (TRAF4), mGFP tagged
"NM_004295" in other vectors (7)
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CNY 5,890.00
Cited in 1 publication. |
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Synonyms | CART1; MLN62; RNF83 |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC200345).
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Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_004295 |
ORF Size | 1410 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_004295.3 |
RefSeq Size | 2902 bp |
RefSeq ORF | 1413 bp |
Locus ID | 9618 |
UniProt ID | Q9BUZ4 |
Domains | zf-TRAF, RING, MATH |
Protein Families | Druggable Genome |
Protein Pathways | Pathways in cancer, Small cell lung cancer |
MW | 53.5 kDa |
Gene Summary | This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation
,Yu, X;Li, W;Liu, H;Deng, Q;Wang, X;Hu, H;Xu-Monette, ZY;Xiong, W;Lu, Z;Young, KH;Wang, W;Li, Y;,
J Hematol Oncol
,PubMed ID 32357935
[TRAF4]
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Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC200345 | TRAF4 (Myc-DDK-tagged)-Human TNF receptor-associated factor 4 (TRAF4) |
CNY 3,656.00 |
|
RC200345L1 | Lenti ORF clone of Human TNF receptor-associated factor 4 (TRAF4), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC200345L2 | Lenti ORF clone of Human TNF receptor-associated factor 4 (TRAF4), mGFP tagged |
CNY 5,890.00 |
|
RC200345L3 | Lenti ORF clone of Human TNF receptor-associated factor 4 (TRAF4), Myc-DDK-tagged |
CNY 5,890.00 |
|
RG200345 | TRAF4 (tGFP-tagged) - Human TNF receptor-associated factor 4 (TRAF4) |
CNY 4,370.00 |
|
SC117456 | TRAF4 (untagged)-Human TNF receptor-associated factor 4 (TRAF4) |
CNY 2,950.00 |
|
SC320675 | TRAF4 (untagged)-Human TNF receptor-associated factor 4 (TRAF4) |
CNY 2,950.00 |